| 1 |  | Iron Man 2 (2010) | $128M | $128M |
| 2 |  | A Nightmare on Elm Street (2010) | $9.12M | $48.5M |
| 3 |  | How to Train Your Dragon (2010) | $6.68M | $201M |
| 4 |  | Date Night (2010) | $5.45M | $81M |
| 5 |  | The Back-up Plan (2010) | $5.03M | $30.1M |
| 6 |  | Furry Vengeance (2010) | $4.48M | $12.1M |
| 7 |  | Clash of the Titans (2010) | $2.5M | $158M |
| 8 |  | Death at a Funeral (2010) | $2.31M | $38.5M |
| 9 |  | Bébé(s) (2010) | $2.16M | $2.16M |
| 10 |  | The Losers (2010/I) | $1.85M | $21.5M |
