| 1 | The Karate Kid (2010) | $55.7M | $55.7M | |
| 2 | The A-Team (2010) | $25.7M | $25.7M | |
| 3 | Shrek Forever After (2010) | $15.8M | $210M | |
| 4 | Get Him to the Greek (2010) | $9.94M | $36.4M | |
| 5 | Killers (2010) | $8.01M | $30.3M | |
| 6 | Prince of Persia: The Sands of Time(2010) | $6.49M | $72.2M | |
| 7 | Marmaduke (2010) | $6.01M | $22.3M | |
| 8 | Sex and the City 2 (2010) | $5.44M | $84.7M | |
| 9 | Iron Man 2 (2010) | $4.52M | $299M | |
| 10 | Splice (2009) | $2.94M | $13.2M |